Familial Hypercholesterolaemia for GPs
Familial Hypercholesterolaemia (FH) is an inherited condition which leads to exceptionally high cholesterol levels, often double and sometimes four times those of the general population (BHF, 2018). 1 in 250 of the general population has FH but many are as yet undiagnosed, leaving individuals at high risk of developing cardiovascular disease and dying suddenly at a premature age from a heart attack. On average, the untreated condition shortens life expectancy by 20-30 years. Early treatment with statins will help to prevent cardiovascular disease, lifestyle modifications (such as physical activity, smoking cessation and alcohol reduction to recommended limits) dietary management and careful monitoring can allow people with FH to achieve the same life expectancy as those without the condition. Cardiovascular disease is the leading cause of mortality worldwide and is expected to keep rising, thus the identification of risk factors is important in its prevention.
· Identification and Awareness
· Genetic Testing
· Cascade Testing
· The Family in FH
· Pedigree Drawing and Family History
· Why Test?
· Ethical Issues
· Primary Care Case Finding
· Treatment Options and Benefits